Human brain cells transplanted into mice in ‘most extensive’ integration ever
Human brain tissue transplanted into mice that lack a key part of their brains can grow to occupy most of the vacant space and wire into the animals’ nervous systems.
That’s according to a study published on 16 September in Nature1, which describes the most extensive integration of human brain cells into an animal so far. The experimental strategy overcomes hurdles that have long stymied researchers studying neuropsychiatric illness in laboratory-grown brain tissue.
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NeuroInk Lab Developmental xenocortication using human-derived organoids in mice Abstract The inaccessibility of human brain tissue limits the study of human development and function, a challenge that human stem-cell-derived neural models are beginning to address1,2.…