🔴 Outcomes of SARS-CoV-2 Reinfection

17June, 2022

We show that compared to people with first infection,
reinfection contributes additional risks of all-cause mortality,
hospitalization,
and adverse health outcomes in the pulmonary and several extrapulmonary organ systems;
the risks were evident in those who were unvaccinated, had 1 shot, or 2 or more shots prior to the second infection;
the risks were most pronounced in the acute phase,
but persisted in the post-acute phase of reinfection, and most were still evident at 6 months after reinfection. Compared to non-infected controls, assessment of the cumulative risks of repeated infection showed that the risk and burden increased in a graded fashion according to the number of infections.
The constellation of findings show that reinfection adds non-trivial risks of all-cause mortality, hospitalization, and adverse health outcomes in the acute and post-acute phase of the reinfection.

@COVIDPapers