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Mendeleev Communications Mendeleev Communications @mendcomm · 358 subscribers
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Novel peroxosolvates of quinolone antibiotics containing large hydrogen peroxide clusters

M. A. Kiseleva🏛, P. V. Prikhodchenko🏛, A. V. Churakov🏛

https://doi.org/10.1016/j.mencom.2024.01.008

Volume 34, issue 1, pages 25–27

7 Citations (Scopus 💻)

Novel class of multicomponent quinolone antibiotics,crystalline hydrogen peroxide adducts of nalidixic acid C12H12N2O3 · H2O2 and ciprofloxacin C17H18F1N3O3 · 5 H2O2, were prepared from highly concentrated hydrogen peroxide, and their structures were determined by X-ray crystallography. The second compound contains decameric H-bonded hydrogen peroxide clusters, which makes this substance one of the richest in hydrogen peroxide among organic peroxosolvates.


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