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Mendeleev Communications Mendeleev Communications @mendcomm · 358 subscribers
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Doxorubicin delivery systems based on polypeptide nanoparticles for subcutaneous administration in cancer therapy

N. N. Sudareva🏛, I. I. Tarasenko🏛, D. N. Suslov, O. M. Suvorova🏛, K. A. Kolbe🏛, G. Y. Yukina, M. L. Tyndyk, Yu. G. Zmitrichenko, E. G. Korzhikova-Vlakh🏛🏛

https://doi.org/10.1016/j.mencom.2024.01.006

Volume 34, issue 1, pages 18–21

8 Citations (Scopus 💻)

Polypeptide-based doxorubicin delivery systems were prepared and their physicochemical and functional properties, such as size, encapsulation efficiency, stability, release of doxorubicin in various media and cytotoxicity, were characterized. An in vivo study revealed an effective reduction of tumor growth when these systems were administered subcutaneously.


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