Fungi are best known for returning dead, organic matter to the Earth, but materials scientists are exploring whether they could someday help our bodies repair, in the form of special hydrogels.

To play a role in biomedical settings, a hydrogel needs a multilayered structure like our own skin, cartilage and muscles. While some engineers are working on synthetic versions that mimic biology, University of Utah scientists have found a hydrogel that literally has a life of its own.

Marquandomyces marquandii is a common species of soil mold, and a promising candidate for the job. This fungus has had a bit of an identity crisis, being misclassified as Paecilomyces marquandii until it was reassigned to its own genus in 2020. Soon, it may be able to add the role of 'bio-integrated hydrogel' to its resume.

Bio-integrated hydrogels are created from organisms that we know form crosslinked, intricate network structures that may be capable of standing in for our own soft tissues.

"Hydrogels are regarded as a promising alternative for applications in tissue regeneration and engineering, cell culture scaffolds, cell bioreactors, and wearable devices, owing to their ability to closely mimic the viscoelastic properties of soft tissues," writes lead author Atul Agrawal, an engineer at the University of Utah, and his collaborators.