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The evolving landscape of drug targets

https://www.nature.com/articles/s41573-026-01530-3

In this Review, we map and quantify key elements of these changes over the past 25 years, such as trends in the number and type of targets through which drugs mediate their therapeutic effects, which now include 686 biomolecules modulated by 1,702 drugs.


📕Nature Reviews Drug Discovery (IF=91.2)
Nature The evolving landscape of drug targets Nature Reviews Drug Discovery - Advances in areas including genomics, automation and data science, as well as the diversification of therapeutic modalities, have led to a substantial expansion of...
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