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The past, present and future of self-driving laboratories

https://www.nature.com/articles/s41570-026-00847-2

This Review traces the evolution of self-driving laboratories and examines the structural asymmetries that limit their maturation into shared scientific infrastructure. We frame the next phase of the field around three interdependent requirements: scalability, generalizability and provenance-complete experimentation.

Realizing collective scientific superintelligence will require SDLs that reliably scale throughput, transfer workflows and learned models across laboratories and scientific domains and capture end-to-end experimental data and metadata from precursor preparation through synthesis, characterization and performance evaluation.

Achieving this transition will depend on interoperable data and metadata standards, modular and integrable experimental hardware, and trustworthy artificial intelligence agents that reason under uncertainty within rigorous safety and ethical boundaries.


📕Nature Reviews Chemistry (IF=50.3)
Nature The past, present and future of self-driving laboratories Nature Reviews Chemistry - Self-driving laboratories integrate automation, robotics and artificial intelligence to accelerate chemical discovery. This Review charts their evolution from bespoke...
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