Ulugbek Baymuradov — From Gene to Medicine: Retracing a Cancer Drug's Discovery with AlphaFold and Free Genomics Tools
Ulugbek traced the real story of one cancer drug — trastuzumab (Herceptin) — from the discovery of the HER2 gene in 1985 all the way to today's next-generation antibody drugs, showing the free tools scientists actually use at every step along the way.
1. Breast cancer is the #1 cancer among women in all five Central Asian countries — and about 1 in 5 cases is HER2-positive, exactly the kind this drug targets.
2. There are 1,735 trastuzumab clinical trials registered worldwide — only 2 in Kazakhstan, and 0 in Uzbekistan and the other three countries.
3. Every step of drug discovery now has a free tool anyone can try: cBioPortal for genes, UniProt and AlphaFold for proteins, RCSB PDB in 3D, DepMap for cells, and ClinicalTrials.gov for real-world trials.
Ulugbek has also shared valuable materials and exciting competitions for our participants. Thank you, Ulugbek, for your contribution and support!
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