This research poster introduces Krivelian, a novel line of mutant mice exhibiting congenital ataxia developed at Lobachevsky University. Beginning around twelve to fourteen days after birth, these mice display distinct motor impairments including altered gait, compromised movement coordination, tail hypertonus, and heightened anxiety. Although these neurological deficits manifest early in life and progressively worsen by twenty-four weeks, the overall lifespan of the mice remains unaffected, and they retain mobility throughout their lives. Behavioral assessments, such as the pole test, neurological status evaluation, and foot fault test, confirmed a marked decline in coordination and motor function compared to control groups. Whole-genome sequencing identified three previously unknown genetic variants in these mice, two of which are located in the Grm1 and Syne1 genes associated with spinocerebellar ataxias. Overall, the Krivelian mouse line provides a stable and highly reproducible model of neuromotor deficiency, serving as a valuable platform for future neurological research.