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Forwarded from Miss Pink

And then there’s this alleged isolated case of Krabbe disease following Covid vaccination 👀
“The ‘wine glass’ appearance refers to a characteristic sign wherein the coronal T2-weighted imaging (T2-WI) sequences show hyperintensities of the corticospinal tracts bilaterally.1This sign has been infrequently observed in motor neuron diseases,1 and rarely in adult-onset leukodystrophies (especially in Krabbe disease),2,3 osmotic demyelination syndrome (ODS),4celiac disease,5 Lyme neuroborreliosis,6 and human T-cell lymphotropic virus type 1 (HTLV-1) infection,7 among others. The ‘wine glass’ sign has not been described following receipt of any type of vaccine. We herein report the first case of ‘wine glass’ pattern following COVISHIELD vaccination (ChAdOx1 nCoV-19; recombinant, replication-deficient chimpanzee adenovirus vector vaccine).

Case report
A 47-year-old previously healthy man from rural West Bengal (India) was brought to the emergency department with abrupt onset rapidly progressive stiffness of bilateral lower limbs and clumsiness of both upper limbs for the last five days. It was associated with slurring of speech, gait unsteadiness, and behavioral changes in the form of inappropriate laughter, crying spells and inappropriate intermittent anger outbursts.”

https://www.elsevier.es/es-revista-neurologia-295-articulo-wine-glass-sign-following-covid-19-S021348532200007X
www.elsevier.es ‘Wine Glass’ sign following COVID-19 vaccination in a previously healthy adult The ‘wine glass’ appearance refers to a characteristic sign wherein the coronal T2-weighted imaging (T2-WI) sequences show
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