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📄 Spatiotemporally Programmable Chaperone‐Mediated Autophagy Activation Disarms the Senescence‐Immunity Axis for Targeted Intervertebral Disc Regeneration

📝 هیدروژل پاسخده به ROS با رهایش ترتیبی تاننیک اسید و EVs، محور پیری-ایمنی را در تخریب دیسک بینمهرهای مهار کرده و بازسازی را در مدل موش بهبود میدهد.

📚 Journal: Advanced Functional Materials #AdvancedFunctionalMaterials
📅 Date: 2026-10-14
🔬 Research Article
🔗 10.1002/adfm.79009

🏷 intervertebral disc degeneration · chaperone-mediated autophagy · senescence-immunity axis · ROS-responsive hydrogel · targeted EVs
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