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Post #75910 10
📄 Hydration Changes are Essential for Efficient Breakdown of Faropenem by the L1 Metallo-β-lactamase

📝 شبیه‌سازی QM/MM نشان می‌دهد تغییرات هیدراتاسیون در جایگاه فلزی برای آبکافت کارآمد فاروپنم توسط آنزیم L1 متالو-بتالاکتاماز ضروری است.

📚 Journal: ACS Catalysis #ACSCatalysis
📅 Date: 2026-10-10
🔬 Research Article | 🔓 Open Access | 📥 PDF
🔗 10.1021/acscatal.6c04439

🏷 metallo-beta-lactamase · faropenem · QM/MM · hydration · antibiotic resistance
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