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Post #74270 12
📄 A Radical Addition–Diradical Coupling Switch Unifies Cytochrome P450-Catalyzed Diketopiperazine Dimerization

📝 این پژوهش مکانیسم جفت‌شدن دیرادیکالی را برای دیمریزاسیون DKP کاتالیزشده توسط P450 روشن کرده و چهار حالت اتصال متفاوت را بازبرنامه‌ریزی می‌کند.

📚 Journal: Journal of the American
Chemical Society #JACS
📅 Date: 2026-10-05
🔬 Research Article
🔗 10.1021/jacs.6c16809

🏷 cytochrome P450 · diketopiperazine dimerization · diradical coupling · protein engineering · QM/MM
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