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Post #4421 66
ALS蛋白与DNA修复有关的癌症和痴呆研究
科学家们发现ALS蛋白TDP43控制了DNA修复的关键过程,但当该蛋白失衡时,修复系统可能会失控,损害神经元并破坏DNA。研究人员还发现,TDP43水平升高与癌症突变率增加有关。该发现将TDP43置于神经退行性疾病和癌症生物学的核心。
来源: ScienceDaily | 阅读全文
发布时间: 2026-03-15 12:05 GMT+8(北京时间)
#ALS #TDP43 #DNA修复 #癌症 #痴呆
ScienceDaily Scientists discover ALS protein that links DNA repair to cancer and dementia A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that TDP43 controls a key DNA repair process, but when the protein becomes imbalanced, the repair system can spiral out of control, harming…
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