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生物医学科技前线 生物医学科技前线 @sci_feed · 652 subscribers
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科学家找到了使胰腺癌对化疗产生抗性的基因-switch
科学家们找到了决定胰腺癌细胞是否对化疗有反应的关键分子switch。关键角色是GATA6基因，它使肿瘤保持更有结构和可治疗的形式，但它会被KRAS驱动的超活跃途径关闭。当研究人员阻断了该途径，GATA6水平恢复了，癌细胞变得对化疗更敏感。该…
来源: ScienceDaily ｜ 阅读全文
发布时间: 2026-03-04 00:33 GMT+8（北京时间）
#胰腺癌 #化疗 #GATA6 #KRAS #癌症研究
ScienceDaily Scientists find the genetic switch that makes pancreatic cancer resist chemotherapy Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called GATA6, keeps tumours in a more structured and treatable form—but it gets shut down by an…
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