The Impact of miR-155-5p on Myotube Differentiation: Elucidating Molecular Targets in Skeletal Muscle Disorders
New Paper by NIIMA Interest Group
🔹An emerging property of muscle miRNAs is the cooperative regulation of transcriptional and epitranscriptional events controlling muscle phenotype.
🔹Through in silico and in vitro approaches, authors identify distinct transcriptional profiles induced by miR-155-5p in muscle cells.
🔹Analysis indicated that miR-155 regulates a set of transcripts, including Aldh1l, Nek2, Bub1b, Ramp3, Slc16a4, Plce1, Dync1i1, and Nr1h3.
▫️Source: https://doi.org/10.3390/ijms25031777
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