Amir Sanati-Nezhad
Assistant Professor of Mechanical and Biomedical Eng/ University of Calgary

Title: The nexus of computational and experimental models of tumor microenvironment

Abstract:
Emerging evidence shows that endothelial cells are not only the building blocks of vascular networks that enable oxygen and nutrient delivery throughout a tissue but they also serve as a rich resource of angiocrine factors. The endothelial cells, in terms of cancer, play key roles in determining cancer progression and response to anti-cancer drugs. Furthermore, the endothelium-specific deposition of extracellular matrix is a key modulator of the availability of angiocrine factors to both stromal and cancer cells...

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