For the first time in history, doctors are about to tell aged human cells to become young again, and watch what happens.
Every cell keeps the same DNA its whole life. What changes is the epigenome, the layer of chemical marks that switches genes on and off. With age those marks drift, and cells lose the memory of how to be young. Yamanaka's Nobel-winning work showed four factors can rewind a cell all the way back to a stem cell.
A therapy called ER-100 does something gentler. It uses only three of those factors and leaves out the fourth, riskier one, rolling the cell's clock backward without erasing what it .
Innerstanding with Devan & Aurora πΊ
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