Astragalus root is also hepatoprotective, a class of herbs that protect hepatocytes (liver cells) from free radical damage. It is protective against the exposure of environmental toxins, particularly carcinogenic agents such as carbon tetrachloride.
A 2016 study showed that a mixture of Myristica fragrans, Astragalus membranaceus and Poria cocos was effective in reducing alcohol-induced acute liver toxicity. The study showed a decrease in liver enzymes and an increase in SOD which demonstrates the effectiveness of Astragalus root in supporting liver detoxification and decreasing damage.