There are two key phases of liver detoxification; phase 1 and phase 2.

Phase 1 is bioactivation and is all about the transformation of fat soluble compounds into water soluble compounds. Phase 1 transforms caffeine, OTC drugs, ibuprofen, histamines, hormones, tobacco and insecticides. This is dependent and carried out by Cytochrome P450 enzymes, a family of enzymes who enable the transformation of these compounds.
Phase 2 are our 6 conjugation pathways – Glucuronidation, Glutathionation, Sulfation, Methylation, Glycination and Acetylation. These pathways see organophosphates, pesticides, alcohol, toxic metals, penicillin, sex and stress hormones converted into different compounds through 1 of these pathways to be eliminated by the bodies key emunctory organs; the lungs (breath), skin (sweat), kidneys (urine) and large intestine (poop).