At the Alcor facility in Arizona, more than 150 disembodied heads reportedly lie in cryogenic chambers, preserved in hopes that future medical advances can bring these brains back to life in new bodies. Given that scientists still cannot revive a cryogenically preserved brain, why do patients bother with cryonics at all? Why couldn't these heads just be stitched onto new bodies in the present day, when they're still fresh? In other words, why isn't a brain transplant possible?
Dr. Max Krucoff, an assistant professor of neurosurgery at the Medical College of Wisconsin, would rather describe such a procedure as a body transplant. Unlike a patient who receives a donor heart or liver, transplanting a brain into a patient's body would make them "a completely new human being," he told Live Science. "Your agency, your identity, is contained within your brain".
Semantics aside, Krucoff said this transplant is currently impossible because surgeons cannot yet forge signaling connections between nerves in the central nervous system, which includes the brain and spinal cord. Transplanted peripheral nerves, or the nerves that branch off throughout the body beyond the brain and spinal cord, can eventually communicate with their new neighbors, since these nerve cells can regenerate. There is less evidence that the adult human central nervous system can generate fresh neurons, and if it does, it's to a limited degree. Neurons can form new connections throughout a person's lifetime, which is how learning is encoded, but scientists do not understand this pathway well enough to exploit it for a transplant.
Even a partial brain transplant, such as a cerebellum swap, is out of the question for now. In the case of the cerebellum, the structure is home to millions of specialized neurons called Purkinje cells, each of which receives signals from thousands of other neurons. "The number of connections is exponential," Krucoff said. "That's way beyond our capacity."
Source: Live Science
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