Empty Set of Ideas

Lateralized sleeping positions in domestic cats (2025)
>cell press
>12 авторов просто считают спящих котов

украдено из labrats

Neuropeptides specify and reprogram division of labor in the leafcutter ant Atta cephalotes (2025)

Social insects offer powerful models to investigate mechanisms of elaborate individual behaviors comprising a cooperative community. Workers of the leafcutter ant genus Atta are extreme examples of behavioral segregation among phenotypically distinct worker types. We utilize this worker system to test the molecular underpinnings of behavioral programming and the extent of plasticity to reprogramming. We identify specific neuropeptides mediating worker division of labor in A. cephalotes, finding two neuropeptides associated with characteristic behaviors of leaf cutting and of brood care. Genetic knockdown or injection of these neuropeptides led to a stark gain or loss of each behavior and to transcriptomic shifts toward gene pathways expressed in the natural castes. We also reveal global similarities between worker transcriptomes of the eusocial mammal, the naked mole-rat H. glaber, with orthologous A. cephalotes workers. This work underscores the essential function of neuropeptides in establishing complex social behavior and a remarkable plasticity among individual behavioral types.

"However, we did notice, and documented in our paper, instances when the DGM hacked its reward function. For example, we had cases where it hallucinated that it was using external tools, such as a command line tool that runs unit tests that determine if the code is functioning properly. It faked a log making it look like it had run the tests and that they had passed, when in fact they were never run! Because these logs become its context, it later mistakenly thought its proposed code changes had passed all the unit tests."

https://sakana.ai/dgm/

New phytoplasma effector: 50 shades of green (2024)

Phytoplasmas are bacteria that thrive in both plants and insects, manipulating their hosts to enhance their own survival and spread, while causing severe harm to plants. Despite their small genomes (0.53–1.35 Mb), they induce dramatic plant developmental changes, such as excessive branching ("witches’ brooms") and floral organ transformations (phyllody), by secreting effector proteins: SAP05, SAP11 and SAP54.

plants vs phytoplasma finally realized in Cell Press

Snake venom protection by a cocktail of varespladib and broadly neutralizing human antibodies (2025)

мужика 20 лет кусали самые ядовитые змеи со всего земного шара, а теперь из него делают универсальный антидот и написали статью в Q1


Highlights
• We report a systematic method for the construction of a broad-spectrum snake antivenom
• Broadly neutralizing antitoxin antibodies were identified from a venom-immune subject
• Broad toxin neutralization involved recognition of conserved toxin-receptor interfaces
• A 3-agent cocktail blocked envenomation by 19 diverse WHO Category 1 and Category 2 snakes

https://www.science.org/content/article/getting-drunk-fly

https://www.palatinate.org.uk/what-can-intoxicated-flies-teach-us-about-alcoholism/

инебриометр (англ. inebriometer) — идейный родственник "хроматографии", но только из пьяных мух, где распределение по уровням связано с тем, насколько хорошо усваивают алкоголь конкретные особи дрозофил: чем ниже, тем хуже. Первые эскизы прибора относятся к уже пыльным 80м

вот тут уже статья про ингаляционные анестетики в целом, тестируемые инебриометром

картинка из работы "Flying Together: Drosophila as a Tool to Understand the Genetics of Human Alcoholism" (2020)

Patterning on Living Tardigrades (2025)

технология для нанесения графити на тихоходок

" This approach provides new insights into tardigrades’ resilience and has potential applications in cryopreservation, biomedicine, and astrobiology."

Novel color via stimulation of individual photoreceptors at population scale (2025)

файналли, новые цвета и рукотворный тюнинг сетчатки

"We introduce a principle, Oz, for displaying color imagery: directly controlling the human eye’s photoreceptor activity via cell-by-cell light delivery. Theoretically, novel colors are possible through bypassing the constraints set by the cone spectral sensitivities and activating M cone cells exclusively. In practice, we confirm a partial expansion of colorspace toward that theoretical ideal. Attempting to activate M cones exclusively is shown to elicit a color beyond the natural human gamut, formally measured with color matching by human subjects. They describe the color as blue-green of unprecedented saturation. Further experiments show that subjects perceive Oz colors in image and video form. The prototype targets laser microdoses to thousands of spectrally classified cones under fixational eye motion. These results are proof-of-principle for programmable control over individual photoreceptors at population scale."

всегда знал, что во всем виноват Unity

Everyone knows your location: tracking myself down through in-app ads

Everyone knows your location, Part 2: try it yourself and share the results

Soft Biological Actuators for Meter-Scale Homeostatic Biohybrid Robots (2025)

1на1 с робопсом бостон динамикс


"Skeletal muscle’s elegant protein-based architecture powers motion throughout the animal kingdom, with its constituent actomyosin complexes driving intra- and extra-cellular motion. Classical motors and recently developed soft actuators cannot match the packing density and contractility of individual muscle fibers that scale to power the motion of ants and elephants alike. Accordingly, the interdisciplinary fields of robotics and tissue engineering have combined efforts to build living muscle actuators that can power a new class of robots to be more energy-efficient, dexterous, and safe than existing motor-powered and hydraulic paradigms. Doing so ethically and at scale─creating meter-scale tissue constructs from sustainable muscle progenitor cell lines─has inspired innovations in biomaterials and tissue culture methodology. We weave discussions of muscle cell biology, materials chemistry, tissue engineering, and biohybrid design to review the state of the art in soft actuator biofabrication. Looking forward, we outline a vision for meter-scale biohybrid robotic systems and tie discussions of recent progress to long-term research goals."

Perforation-type anchors inspired by skin ligament for robotic face covered with living skin (2024)

смаайл

Highlights
• Perforation-type anchor is proposed to adhere living skin to robotic surfaces
• Proposed anchor mimics human skin ligaments by gelling skin tissue via perforations
• 3D facial mold and 2D skin robot covered with living skin are created

Подробная история мегаломанического проекта Cyc (from "encyclopedia"), создававшего полвека логический ИИ вручную

"Obituary for the greatest monument to logical AGI. After 40 years, 30 million rules, 200 million dollars, 2000 person-years, and many promises, Cyc has failed to reach intellectual maturity, and may never will. Exacerbated by the secrecy and insularity of Cycorp, there remains no evidence of its general intelligence."

https://yuxi-liu-wired.github.io/essays/posts/cyc/

A machine learning library written in pure LaTeX

finally, Overleaf turns into a free cloud compute service for training models

развивая сыпучий топик: атлас песка (2025)


песок можно скачать по ссылке:
https://sand-atlas.scigem.com/

the pill-pile model (2021) — арт-вариация классической работы 1996 года "Avalanche dynamics in a pile of rice"

https://vimeo.com/595481455