Stripe processes over 1,145 pull requests daily through three key strategies: organizing into small autonomous teams that create micro-PRs (under 150 lines), implementing lightning-fast CI pipelines (2-4 minutes) with automated testing and auto-merge capabilities, and using feature flags with instant rollback mechanisms for safe deployments. The approach emphasizes breaking large features into small, reviewable increments, automating manual coordination tasks, and decoupling deployment from release through granular feature controls.