Predicting survival from colorectal cancer histology slides using #deeplearning

1. They conducted the study because:
• Colorectal cancer (CRC) is a common disease with a variable clinical course, and there is a high clinical need to more accurately predict the outcome of individual patients.
• For almost every CRC patient, histological slides of tumor tissue are routinely available.
• Deep learning can be used to extract information from very complex images, and we hypothesized that deep learning can predict clinical outcome directly from histological images of CRC.

2. What did the researchers do and find?
• We trained a deep neural network to identify different tissue types & demonstrated that it can decompose complex tissue into its constituent parts and thereby showed that this score improves survival prediction compared to the SOTA avaiable.

3. Conclusion
• Deep learning is an inexpensive tool to predict the clinical course of CRC patients based on ubiquitously available histological images.
• Prospective validation studies are needed to firmly establish this biomarker for routine clinical use.

☞ Link to research

#healthcare #AI #machinelearning

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